开网店的英文表达是 "open an online store"。来源是由 "open"（开）和 "online store"（网店）两个词组合而成。

下面是一些可能的例句，包括中文翻译：

I want to open an online store to sell my handmade crafts. 我想开一个网店来出售我的手工艺品。

He decided to open an online store to reach a wider audience. 他决定开一个网店，以此来拓展更广泛的受众。

She has been running an online store for a year and it has been doing well. 她已经经营网店一年了，业务进展顺利。